Isotype-specific agglutination-PCR (ISAP): A sensitive and multiplex method for measuring allergen-specific IgE
نویسندگان
چکیده
منابع مشابه
Induction and regulation of allergen-specific IgE
The immune response is characterized by an initial rapid activation of the innate defence system, geared at recognizing common structures shared by many microorganisms. This innate immune response is a prerequisite to mount a highly antigenspecific adaptive immune response consisting of T-cell differentiation into effector subsets and B-cell differentiation into antibody-secreting plasma cells....
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Using a microarray platform for allergy diagnosis allows for testing of specific IgE sensitivity to a multitude of allergens, while requiring only small volumes of serum. However, variation of probe immobilization on microarrays hinders the ability to make quantitative, assertive, and statistically relevant conclusions necessary in immunodiagnostics. To address this problem, we have developed a...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2018
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2017.11.021